Integrative Pathway Genomics of Lung Function and Airflow Obstruction Sina
نویسندگان
چکیده
Sina A. Gharib, Daan W. Loth, María Soler Artigas, Timothy P. Birkland, Jemma B. Wilk, Louise V. Wain, Jennifer Brody, Maen Obeidat, Dana B. Hancock, Wenbo Tang, Rajesh Rawal, H. Marike Boezen, Medea Imboden, Jennifer E. Huffman, Lies Lahousse, Alexessander C. Alves, Ani Manichaikul, Jennie Hui, Alanna C. Morrison, Adaikalavan Ramasamy, Albert Vernon Smith, Vilmundur Gudnason, Ida Surakka, Veronique Vitart, David M. Evans, David P. Strachan, Ian J. Deary, Albert Hofman, Sven Gläser, James F. Wilson, Kari E. North, Jing Hua Zhao, Susan R. Heckbert, Deborah L. Jarvis, Nicole Probst-Hensch, Holger Schulz, R. Graham Barr, Marjo-Riitta Jarvelin, George T. O’Connor, Mika Kähönen, Patricia A. Cassano, Pirro G. Hysi, Josée Dupuis, Caroline Hayward, Bruce M. Psaty, Ian P. Hall, William C. Parks, Martin D. Tobin, Stephanie J. London, CHARGE Consortium; SpiroMeta Consortium.
منابع مشابه
Integrative pathway genomics of lung function and airflow obstruction.
Chronic respiratory disorders are important contributors to the global burden of disease. Genome-wide association studies (GWASs) of lung function measures have identified several trait-associated loci, but explain only a modest portion of the phenotypic variability. We postulated that integrating pathway-based methods with GWASs of pulmonary function and airflow obstruction would identify a br...
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